St. Therese of Lisieux was a young Carmelite who became known as the Little Flower of Jesus for her life of simple, practical holiness. Although not well known in her life time, her spiritual memoir “The Story of a Soul” made her and her spirituality so popular and well-regarded that Pope Pius X called her “the greatest saint of modern times.” 
St. Frances X. Cabrini was an Italian-American who founded the Missionary Sisters of the Sacred Heart of Jesus to provide education, health care and other services to the poor. She desired to go to China as a missionary, but the Pope urged her to go instead to New York to support the many poor Italians flooding into the country as immigrants. She established schools, orphanages and a hospitals.